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Eur J Cardiothorac Surg 2007;32:559. doi:10.1016/j.ejcts.2007.01.053
Copyright © 2007, European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved
Editorial |
University Hospital Schleswig-Holstein, Campus Kiel, Germany
* Corresponding author. (Email: jcremer@kielheart.uni-kiel.de).
| The first 20% of the full text of this article appears below. |
Adjunctive application of fibrin sealant in coronary artery bypass graft (CABG) surgery has been established over years for various indications, such as bleeding from distal or proximal anastomoses, fixation of the bypass course, diffuse epicardial bleeding, sealing of the IMA-bed, and intrasternal application for profound bone marrow bleeding. Moreover, fibrin sealant has been used in surgical fields with diffuse bleeding, e.g. in cardiac re-operations, for pre-clotting of Dacron prostheses, in thoracic organ transplantation, aortic aneurysm surgery, and in complex congenital heart surgery.
The publications of Görler et al. [1] and Lamm et al. [2] from distinguished heart centers are presenting data showing an unfavorable risk–benefit relation based on safety issues after the application of Tissucol® Duo S in CABG surgery. Both papers assess a
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