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Eur J Cardiothorac Surg 2007;32:950. doi:10.1016/j.ejcts.2007.09.020
Copyright © 2007, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
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Alfredo Cesario
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Letters to the Editor

Inflammation and thoracic surgery: a complex interaction

Laura Palearia, Patrizia Russoa, Alfredo Cesariob,c,*, Pierluigi Granoneb

a Lung Cancer Unit, National Cancer Research Institute, Genoa, Italy
b Thoracic Surgery Unit, Catholic University, Rome, Italy
c Pulmonary Rehabilitation, IRCCS San Raffaele, Rome, Italy

Received 5 September 2007; accepted 21 September 2007.

* Corresponding author. Address: General Thoracic Surgery, Catholic University, Largo A. Gemelli 8, 00168 Rome, Italy. Tel.: +39 06 30156326; fax: +39 03 3051162. (Email: alfcesario@yahoo.com).

Key Words: Inflammation • COPD • Apoptosis • C-reactive protein • Lung cancer

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We appreciated the reading of the work of Amar et al. [1]. The authors reported data suggesting that markers of inflammation such as C-reactive protein (CRP) and IL-6 can help to classify patients who are at high risk for major postoperative complications (PC) following thoracic surgery. Systemic inflammation is thus considered to be important in the pathogenesis of important PC. Defining the precise inflammatory response represents a sensitive issue, frequently debated within scientific community. Plasma levels of cytokines or CRP are probably not sufficient to determine whether a patient or experimental animal is hyper-inflammatory or hypo-inflammatory. If only the . . . [Full Text of this Article]




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Home page
 Eur. J. Cardiothorac. Surg.Home page
D. Amar, B. Park, and P. M. Heerdt
Reply to Paleari et al.
Eur. J. Cardiothorac. Surg., December 1, 2007; 32(6): 950 - 951.
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Copyright © 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.