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Eur J Cardiothorac Surg 2008;33:949-950. doi:10.1016/j.ejcts.2008.02.010
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
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Joseph Patrick McGoldrick
Ralph W. White
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Letters to the Editor

Fibrin sealant in coronary artery surgery – the devil is always in the detail!

Joseph Patrick McGoldrick*, Ralph W. White

Department of Cardiothoracic Surgery, Yorkshire Heart Centre, Leeds General Infirmary, Leeds LS1 3EX, United Kingdom

Received 3 December 2007; accepted 7 February 2008.

* Corresponding author. Tel.: +44 113 392 6901; fax: +44 113 392 6657. (Email: JoeMcGoldrick@doctors.org.uk).

Key Words: Coronary artery surgery • Surgical sealants • Myocardial infarction

The first 20% of the full text of this article appears below.

Lamm et al. [1] conclude ‘the intraoperative use of fibrin sealant posed an increased risk of myocardial damage or death after coronary artery surgery’. The paper is thought provoking and flawed.

• Vital information is lacking on indications, timing and utilisation of Tissucol® Fibrin sealant. The authors state that ‘in most cases’ they had no idea how, where, why, or when a sealant was clinically employed nor how many patients exposed to sealant entered the analysis.
• There is no basis supporting their assertion of a causal relationship between sealant use and graft thrombosis.
• There was no equivalence between . . . [Full Text of this Article]




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Home page
 Eur. J. Cardiothorac. Surg.Home page
P. Lamm, G. Juchem, and B. Reichart
Reply to McGoldrick and White.
Eur. J. Cardiothorac. Surg., May 1, 2008; 33(5): 950 - 950.
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Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.