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Eur J Cardiothorac Surg 2008;33:1161-1162. doi:10.1016/j.ejcts.2008.03.021
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
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Letters to the Editor

Re: Perivascular tissue of internal thoracic artery releases potent nitric oxide and prostacyclin-independent anticontractile factor

Michael Richard Dashwooda,*, Domingos S.R. Souzab, Maria S. Fernández-Alfonsoc

a Clinical Biochemistry (First Floor), Royal Free and University College Medical School, Pond Street, London NW3 2QG, United Kingdom
b Örebro University Hospital, SE-701 85 Örebro, Sweden
c Instituto Pluridisciplinar, Universidad Complutense, Madrid, Spain

Received 22 February 2008; accepted 19 March 2008.

* Corresponding author. Tel.: +44 20 7794 0500; fax: +44 20 7830 2235. (Email: m.dashwood@medsch.ucl.ac.uk).

Key Words: CABG • Perivascular tissue • Nitric oxide • Saphenous vein • Internal thoracic artery

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We read with interest the recent article by Malinowski et al. [1] on the release of a soluble anticontractile factor from perivascular tissue (PVT) of the internal thoracic artery (ITA). In this study the authors show that the PVT surrounding the ITA, the ‘gold standard’ graft in coronary artery bypass surgery (CABG), releases a nitric oxide (NO) and prostacyclin-independent anticontractile factor. The authors suggest that the presence of an active PVT might explain the functional difference between skeletonised and non-skeletonised ITA and influence vascular function after graft implantation. Possible drawbacks of removing PVT should be taken into account since . . . [Full Text of this Article]




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Home page
 Eur. J. Cardiothorac. Surg.Home page
M. A. Deja and M. Malinowski
Reply to Dashwood et al.
Eur. J. Cardiothorac. Surg., June 1, 2008; 33(6): 1162 - 1163.
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Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.