Eur J Cardiothorac Surg 2008;34:227-228. doi:10.1016/j.ejcts.2008.05.013
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
Cardiac tissue engineering
Axel Haverich*
Division of Thoracic & Cardiovascular Surgery, Hannover Medical School, Hannover, D-30623, Germany
* Corresponding author. (Email: Haverich.Axel@mh-hannover.de).
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Dass ich erkenne, was die Welt im Innersten zusammenhält (that I should recognize what holds the world together at its core) – when Goethe published his Faust, he was inspired by the most recent transdisciplinary scientific discovery at that time, the synthesis of Urea; an organic substance from inorganic sources, hydrogen, and nitrogen. His fantasy was strong enough to imagine reconstructing entire organisms (homunculus), using respective synthetic pathways. Over 200 years later we are getting closer, providing functional tissues for clinical repair, using scaffolds and cells for (re-)generation of organs and parts thereof. This concept is called tissue engineering and cardiovascular medicine plays a pivotal role in this scientific adventure, which will undoubtedly result in avenues towards reconstruction of an individual's own human heart in the years to come. Alles ist einfacher als man denken kann, zugleich verschränkter, als zu begreifen ist (everything . . . [Full Text of this Article]
Copyright © 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier. All rights reserved.