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Eur J Cardiothorac Surg 2003;23:422
© 2003 Elsevier Science NL

Images in cardio-thoracic surgery

Giant thymolipoma in association with myasthenia gravis

Ahmet Cekirdekcia*, Nusret Akpolatb, Erhan Ayana, Mehmet Durana

a Department of Thoracic and Cardiovascular Surgery, Firat University, School of Medicine, 23100 Elazig, Turkey
b Department of Pathology, Firat University, School of Medicine, 23100 Elazig, Turkey

Received 10 April 2002; received in revised form 13 November 2002; accepted 20 November 2002.

* Corresponding author. Tel.: +90-424-2416120; fax: +90-424-2388096
e-mail: ahmetcekirdekci{at}hotmail.com

Key Words: Thymolipoma • Myasthenia gravis

A 25-year-old female patient with myasthenia gravis underwent resection of a giant mass located in the anterior mediastinum that measured 34x18x7 cm and weighed 1,780 g (Fig. 1) . Histologically, the tumor proved to be a thymolipoma (Fig. 2) . The association of myasthenia gravis with giant thymolipoma is rare. Myasthenic symptoms improved significantly after surgery.



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  		Fig. 1. Spiral CT scan reveals a large inhomogeneous anterior mediastinal mass composed of fatty areas which surrounded the heart entirely and extended into both hemithorax.

 


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  		Fig. 2. Photomicrograph of the thymolipoma: mature adipose tissue and thymic tissue with Hassall's corpuscle (->). HE x100.

 




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