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Eur J Cardiothorac Surg 2005;28:506
© 2005 Elsevier Science NL

Letter to the Editor

Reply to Spina et al.Molecular studies in lung cancer patients with chronic obstructive pulmonary diseases

Angel López-Encuentra *

Pneumology Service, Hospital Universitario 12 de Octubre, Avda. Córdoba s/n, 28041 Madrid, Spain

Received 4 May 2005; accepted 9 May 2005.

* Corresponding author. Tel./fax: +34 91 3908492. (Email: lencuent{at}h12o.es).

Key Words: Lung cancer • COPD • Molecular • Surgery

We are grateful to Spina et al. for their comments concerning our work [1]. In accordance with their hypotheses, it is necessary for the molecular aspect of lung cancer to be studied more thoroughly in general and to deepen into certain subpopulations affected with that neoplasia.

Currently, our sample consisting of 2994 cases of lung cancer from the GCCB-S, is being used to measure the expression of over 30 proteins employing the tissue arrays technology [2]. In doing so, we expect to be able to answer some of the questions raised.

References

  1. Lopez-Encuentra A, Astudillo J, Cerezal J, Gonzalez-Aragoneses F, Novoa N, Sanchez-Palencia A, Bronchogenic Carcinoma Cooperative Group of the Spanish Society of Pneumology and Thoracic Surgery (GCCB-S). Prognostic value of chronic obstructive pulmonary disease in 2994 cases of lung cancer. Eur J Cardiothorac Surg 2005;27(1):8-13.[Abstract/Free Full Text]
  2. Conde E, García-Luján R, López-Encuentra A, Sánchez-Céspedes M, López-Rios F. Protein expresión profiles in non-small cell lung cancer. A tissue microarray-based study of 142 cases. Lung Cancer; 2005. In press..




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