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Letters to the Editor |
a Department of Cardiac Surgery, St. Ekaterina University Hospital, 1431 Sofia, Bulgaria
b Department of Anatomy and Histology, Medical University, 1431 Sofia, Bulgaria
Received 7 August 2007; accepted 8 August 2007.
* Corresponding author. Address: Department of Cardiac Surgery, "St. Ekaterina" University Hospital, 52a "P. Slaveikov" blvd, 1431 Sofia, Bulgaria. Tel.: +359 889 700 343. (Email: vassil_papanchev{at}yahoo.com).
Key Words: Cardiac surgery Vessels Variations Cerebral protection
We would like to thank Ellenberger et al. [1] for their interest in our article [2]. The authors added some important comments that were not discussed in detail in our work [2]. We agree with the authors opinion for stepwise multimodality neuroprotective strategy for each separate patient [1]. Such an approach will help to choose the most effective method for cerebral protection and will allow adequate intraoperative follow-up. Nevertheless we must always bear in mind that in some patients such profound preoperative examinations could not be possible, for example, some patients with aortic dissection diagnosed outside a specialized cardiac surgery center. We believe that in such cases bilateral selective cerebral perfusion should be the protective strategy of choice, since it will overcome the variations of circle of Willis, if such are present [2], and it could ensure adequate cerebral blood supply even in patients with uni- or bilateral internal carotid artery stenosis/occlusion.
Our work also stressed the fact that the results derived from animal models of selective cerebral perfusion must not be extrapolated to humans, since the cerebral blood supply of the animals brain is quite different from that in humans, namely the absence of the anterior communicating artery in most of the domestic animals (for example, pigs), extensive anastomoses between extra- and intracranial arteries and presence of variations of the circle of Willis in all species [2].
References
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