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Eur J Cardiothorac Surg 2008;34:1274. doi:10.1016/j.ejcts.2008.08.023
Copyright © 2008, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.
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Letters to the Editor

Reply to Pagès

Yoshimasa Maniwa*

Division of Thoracic Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan

Received 26 August 2008; accepted 27 August 2008.

* Corresponding author. Tel.: +81 78 382 5942; fax: +81 78 382 5959. (Email: maniwa{at}med.kobe-u.ac.jp).

Key Words: Metastatic lung cancer • Lung resection • Metastasectomy

We would like to thank Dr Pagès for his helpful comment [1] on our study [2].

In this study, some limitations remained as you pointed out. Further investigation will provide answers to the questions.

This time, we did not refer the impact of tumor doubling time (TDT) on the outcome after metastasectomy, because we did not have analyzable data about it. However, we also got the impression that short TDT was the sign of uncontrollable disease. I guess the period of careful observation is necessary before metastasectomy to assess such important factors.

Anyway, we need further studies to standardize the indication of lung metastasectomy.

References

  1. Pages O. Pulmonary metastasis resection: is it a question of optimal timing or tumor doubling time?. Eur J Cardiothorac Surg 2008;34:1274.[Free Full Text]
  2. Tanaka Y, Maniwa Y, Nishio W, Yoshimura M, Okita Y. The optimal timing to resect pulmonary metastasis. Eur J Cardiothorac Surg 2008;33:1135-1138.[Abstract/Free Full Text]




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