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Eur J Cardiothorac Surg 2009;35:749-750. doi:10.1016/j.ejcts.2009.03.034
Copyright © 2009, European Association for Cardio-thoracic Surgery. Published by Elsevier. All rights reserved.

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Editorial

Clinical databases – a double-edged sword!

Ludwig K. von Segesser*

Department of Cardio-Vascular Surgery, Centre Hospitalier Universitaire Vaudois, CHUV, Rue du Bugnon 46, 1011 Lausanne, Switzerland

* Corresponding author. Tel.: +41 21 314 22 79; fax: +41 21 314 28 79. (Email: Ludwig.von-segesser{at}chuv.ch). (URL: http://www.cardiovasc.net).

Key Words: Coronary artery disease • Aortic valve stenose • Traumatic aortic rupture • Thoracic surgery • Database • Surgeons performance

To make progress it is absolutely necessary to know what we do in order to define when and how to do it best. This is not specific to our fields of interest, i.e. thoracic, cardiac, and vascular surgery, but much more a general issue. As a matter of fact, it is of prime importance to document the status quo, prior to any change, so that the improvement looked for can be assessed, and compared in its proper context. Monitoring our activities also allows for detecting changes in recruitment, severity of disease, the burden of risk factors, the early operative results, the resources used, and the long-term outcome.

For an individual surgeon, it is not sufficient to know his own results. He has to be able to compare them to the results of his group, to the results of other groups in his area, to the results in other countries, and to the results of competing techniques. The latter is a very important issue and can easily be demonstrated, at least for the short term. Even if a surgeon has excellent results with open repair of descending thoracic aortic aneurysms like zero mortality and zero paraplegia, there can be little doubt that endovascular aneurysm repair is less invasive (no thoracotomy), can be realized in local anaesthesia without the pump oxgenator and other adjuncts, without intensive care unit in many cases, and a shorter hospital stay [1]. The difference between the open and the endovascular approach is so self-speaking [2,3], that post-traumatic aortic ruptures are now routinely addressed with endovascular techniques in many centres, and this despite the fact that, to the best of this author's knowledge, no double blind randomized trial with sufficient power has been published.

However, the most powerful factor speaking in favour of endovascular repair is patient's preference: nobody wants to have his chest split in two if almost similar results can be realized without opening it. The surgeons had to learn this the hard way, with the increasingly popular interventional treatment of coronary artery disease, where the less invasive initial approach with percutaneous angioplasty and stenting with proven need for re-intervention is put in the balance against the repeatedly proven superior long-term outcome of arterial revascularization [4–6]. Even if many surgical centres have been able to keep their volume relatively stable, invasive cardiology has grown continuously over the years and consistently increased its market share.

It has to be remembered here that the next battle is just around the corner. It is the trans-catheter (aortic) valve replacement in trans-femoral versus trans-apical [7,8] or trans-subclavian fashion [9]. There can be no doubt that it is of prime importance to get involved in this field early on. As mentioned above, for surgeons doing endovascular aneurysm repair, reaching from the groin right into the aortic arch, having guide wires parked in the left ventricle with the stiffer part of the wire in the ascending aorta in order to get the covered stent graft into the horizontal part of the arch [10], the aortic valve has already been crossed. Obviously, the main issue here is less about how to do it and what the outcome is, but much more about who does it.

Considering the context outlined above, the publications in this issue about a European Thoracic Database [11], a Surgeon Performance Index [12,13], and Risk Prediction in Coronary Surgery [14,15] are both welcome and worrisome. Although it is good to know what works best, it is good to remember that the lesser best may be rightly or wrongly used in various fashions, and wanted or unwanted harm can provoke consequences of unpredictable dimensions.

This brings up another point which is the illusion of so-called anonymized information in databases. For those interested in the field no such thing exists, and databases are just like an open book. This is due to the fact that many numbers speak for themselves, because everybody knows who has the largest series overall, and who has the largest series for specific procedures [8]. It is also known who has the smallest program, the first case, a specific pattern of procedures, clinical pathways, referral, and, last but not least, outcome.

As a result, the set-up of clinical databases, registries, and data pools becomes a major issue in order to prevent, for example, unauthorized use of non-validated data out of context. As an illustration can be cited the new data about hospital performance that were made available just one day ago in Zurich, Switzerland
(http://www.nzz.ch/nachrichten/zuerich/der_messerscharfe_spitalvergleich_bleibt_eine_illusion_1.2233746.html)

showing a mortality rate after re-infarction of 50% in one hospital, indeed, a worrisome finding, certainly bad enough for headlines if required. However, further analysis revealed that in this institution there had been only two such cases, and that the deceased patient was 93 years old: obviously, a fatal event for that patient and sad for his family, but well within the life expectancy for elderly patients with coronary artery disease.

The wisdom of Socrates (Greece 469 BC–399 BC) may be remembered here for database and similar reports. His three filter test was about checking whether news was true, good, and useful? Reports, being neither true, nor good, nor useful, were not welcome for Socrates, and this has not really changed since!

Read on pages 751–773 [11–15]

References

  1. Xenos ES, Minion DJ, Davenport DL, Hamdallah O, Abedi NN, Sorial EE, Endean ED. Endovascular versus open repair for descending thoracic aortic rupture: institutional experience and meta-analysis. Eur J Cardiothorac Surg 2009;35:282-286.[Abstract/Free Full Text]
  2. Dick F, Hinder D, Immer FF, Savolainen H, Do DD, Carrel TP, Schmidli J. Thoracic endovascular aortic repair: impact of urgency on outcome and quality of life. Eur J Cardiothorac Surg 2009;35:96-103.[Abstract/Free Full Text]
  3. Vucetic B, Hudorovic N, Lovricevic I. Apologia for change in management of blunt rupture of the thoracic aorta. Eur J Cardiothorac Surg 2008;34:469-470.[Free Full Text]
  4. Goy JJ, Eeckhout E, Moret C, Burnand B, Vogt P, Stauffer JC, Hurni M, Stumpe F, Ruchat P, von Segesser L, Urban P, Kappenberger L. Five-year outcome in patients with isolated proximal left anterior descending coronary artery stenosis treated by angioplasty or left internal mammary artery grafting. A prospective trial. Circulation 1999;99(June (25)):3255-3259.[Abstract/Free Full Text]
  5. Goy JJ, Kaufmann U, Hurni M, Cook S, Versaci F, Ruchat P, Bertel O, Pieper M, Meier B, Chiarello L, Eeckhout E, SIMA Investigators 10-year follow-up of a prospective randomized trial comparing bare-metal stenting with internal mammary artery grafting for proximal, isolated de novo left anterior coronary artery stenosis the SIMA (Stenting versus Internal Mammary Artery grafting) trial. J Am Coll Cardiol 2008;52(September (10)):815-817.[Abstract/Free Full Text]
  6. Rastan AJ, Boudriot E, Falk V, Kappetein AP, Borger MA, Serruys PW, Schuler G, Mohr FW. Frequency and pattern of de-novo three-vessel and left main coronary artery disease; insights from single center enrolment in the SYNTAX study. Eur J Cardiothorac Surg 2008;34:376-383.[Abstract/Free Full Text]
  7. von Segesser LK. Direct percutaneous valve replacement: the next step?. Eur J Cardiothorac Surg 2004;26:873-874.[Free Full Text]
  8. Walther T, Falk V, Kempfert J, Borger MA, Fassl J, Chu MWA, Schuler G, Mohr FW. Transapical minimally invasive aortic valve implantation; the initial 50 patients. Eur J Cardiothorac Surg 2008;33:983-988.[Abstract/Free Full Text]
  9. Vahanian A, Alfieri OR, Al-Attar N, Antunes MJ, Bax J, Cormier B, Cribier A, De Jaegere P, Fournial G, Kappetein AP, Kovac J, Ludgate S, Maisano F, Moat N, Mohr F-W, Nataf P, Pierard L, Pomar JL, Schofer J, Tornos P, Tuzcu M, van Hout B, von Segesser LK, Walther T. Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European Association of Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC) in collaboration with the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur J Cardiothorac Surg 2008;34:1-8.[Abstract/Free Full Text]
  10. Siniscalchi G, Tozzi P, Ferrari E, Delay D, Ruchat P, von Segesser L. Endovascular repair of aortic arch aneurysm after achievement of local anesthesia. J Thorac Cardiovasc Surg 2007;133:262-263.[Free Full Text]
  11. Brunelli A, Berrisford RG, Rocco G, Varela G, on behalf of the European Society of Thoracic Surg Database Committee The European Thoracic Database project: composite performance score to measure quality of care after major lung resection. Eur J Cardiothorac Surg 2009;35:768-773.
  12. Hartrumpf M, Claus T, Erb M, Albes JM. Surgeon performance index: tool for assessment of individual surgical quality in total quality management. Eur J Cardiothorac Surg 2009;35:751-758.[Abstract/Free Full Text]
  13. Noyez L. Quality measurement in adult cardiac surgery. A challenge. Eur J Cardiothorac Surg 2009;35:758-759.[Free Full Text]
  14. Antunes PE, Ferrão de Oliveira J, Antunes MJ. Risk-prediction for postoperative major morbidity in coronary surgery. Eur J Cardiothorac Surg 2009;35:760-767.[Abstract/Free Full Text]
  15. Nashef SAM. Predicting morbidity after coronary surgery. Eur J Cardiothorac Surg 2009;35:767.[Free Full Text]




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